Michael Taschner

This study uses a phage endolysin to target Streptococcus salivarius in the gut, revealing niche overlap with butyrate-producing taxa and potential therapeutic benefits.

This study shows that GcrA, a methylation-dependent regulator in Agrobacterium tumefaciens, controls replication timing and cell division by coordinating RepABC origins and divisome gene expression.

This study uses synthetic nanobodies to identify functional regions of the Bacillus subtilis SMC complex, revealing the mid-region of the coiled coil as critical for DNA folding.

The paper investigates how SMG5 licenses SMG6 endonuclease activity in NMD by forming a composite active site with SMG6 PIN domain.

The paper shows that SMC hinge domains selectively allow ssDNA to bypass obstacles during DNA loop extrusion, revealing a conserved mechanism across SMC complexes.

This paper introduces a cloning method for rapidly generating expression constructs of multi-subunit protein complexes in various hosts.

The paper reveals how SMC JET nuclease recognizes and cleaves plasmid DNA by mechanically bending residual unextruded DNA, identifying key structural elements involved in the process.

The paper shows that all eukaryotic SMC complexes extrude DNA asymmetrically, with direction switches observed in cohesin and SMC5/6, linked to NIPBL turnover and stabilized by STAG1.