Jeffrey E. Markowitz

This paper introduces HYFEN, a hydrogel-based endomicroscopy platform that enables flexible, biocompatible, and subcellular-scale fluorescence imaging with improved resolution and performance compared to conventional silica-based fibers.

The paper identifies a spinal neuronal population that autonomously generates a modular motor pattern during jumping in mice, supporting the concept of spinal modular motor control.

The paper develops a red fluorescent calcium indicator, ScaRCaMP, that is compatible with optogenetics due to its high blue-light photostability.

The paper introduces Cleo, a simulation testbed for systems neuroscience experiments, integrating optogenetics, electrophysiology, and closed-loop control to improve experimental design and model validation.

The paper uses MoSeq to analyze behavioral changes in dystonia mouse models after trihexyphenidyl treatment, finding genotype and sex-specific shifts in behavioral structure.

This paper introduces a novel method for high-resolution in vivo kinematic tracking using injectable fluorescent nanoparticles and creates a ground truth dataset for benchmarking markerless keypoint trackers.

The paper resolves a contradiction between striatal reinforcement learning models and SPN synaptic plasticity by showing that iSPN plasticity hinders learning but can be reversed by simultaneous activation of dSPN and iSPN.

The paper uses machine learning to analyze novelty-induced behaviors and finds that dopamine in the striatum correlates with individual variability and is explained by a reinforcement learning model of threat prediction.

This paper introduces tapered optical fibers for dynamic light delivery in brain regions, showing they can illuminate large volumes or specific subregions with adjustable precision.