GeneticsInflammatory Bowel DiseasesPeer-reviewed
A collection of patient-derived intestinal organoid lines reveals epithelial phenotypes associated with genetic drivers of pediatric inflammatory bowel disease
Zahra Shojaei Jeshvaghani, Carmen Argmann, Maaike Hillegonda de Vries…·Edward E. S. Nieuwenhuis
The paper generates intestinal organoids from pediatric IBD patients and controls to study epithelial phenotypes linked to genetic drivers of the disease, identifying gene expression patterns and pathways associated with inflammation.
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