Kira M. Evitts

This study develops 2D and 3D human in vitro neurovascular unit models to investigate microglial interactions with endothelial cells and their role in neurovascular function under inflammatory conditions.

This paper develops a 3D human brain endothelial platform combined with machine learning to identify kinase inhibitors that restore blood-brain barrier integrity in TBI.

This paper introduces a new fluorescent sensor, oROS-HT, for real-time H2O2 monitoring with subcellular resolution and multi-parametric imaging capabilities.

This paper develops a fast, sensitive genetically encoded H2O2 sensor (oROS-G) and demonstrates its use in monitoring H2O2 dynamics in various cell types and models.

This study shows that reducing HDAC2 in hiPSC-derived neurons enhances mitochondrial function and reduces neurotoxic amyloid beta, suggesting HDAC2's role in neuronal maturation and disease.