NeurosciencebioRxivPreprint
Revealing the combined roles of Aβ and tau in Alzheimer's disease via a pathophysiological activity decoder
Lazaro M. Sanchez-Rodriguez, Gleb Bezgin, Félix Carbonell…·Yasser Iturria‐Medina
The paper develops a personalized brain activity model integrating functional MRI, Aβ, and tau-PET to reveal synergistic effects of Aβ and tau on cognitive impairment and neuronal excitability in Alzheimer's disease.