Author

Alex Gibbs

Cardiff UniversityORCID 0000-0003-2416-9145Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:mouse· 2 Organism:human· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Ahmad Habib· 1 shared Alex TonksiD· 1 shared Alhomidi AlmotiriiD· 1 shared Ali AbdelfattahiD· 1 shared Ali Alshahrani· 1 shared Alice Cato· 1 shared Ashleigh S. BoydiD· 1 shared Ayesha Begum· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Ahmad Habib

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMay 13, 2026

Astrocyte immunosuppressive activity in glioblastoma depends on ZEB1 and is counteracted by CXCL14

Mathew Clement, Alex Gibbs, Ayesha Begum…·Florian A. Siebzehnrübl

This study shows that ZEB1 in astrocytes suppresses glioblastoma immunity, and CXCL14 can counteract this effect to enhance T-cell activity and reduce tumor growth.

DOI 10.64898/2026.05.10.724074

mousehuman

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Cancer BiologyStem Cell ReportsPeer-reviewedJul 31, 2025

Impaired DNA damage response and inflammatory signalling underpins hematopoietic stem cell defects in Gata2 haploinsufficiency

Ali Abdelfattah, Ahmad Habib, Leigh-anne Thomas…·Neil P. Rodrigues

This study identifies how Gata2 haploinsufficiency disrupts HSC function and drives pre-leukemic changes through DNA damage and inflammatory signaling, with ASXL1 mutations exacerbating these defects.

4 citations

mouseexperimental assay

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