Tito Candelli

The paper generates a single-cell multi-omics atlas of pediatric bone marrow, revealing age-related shifts in lineage differentiation linked to stromal cell heterogeneity.

CHETAH identifies cell types in scRNA-seq data using hierarchical clustering and reference data, offering accuracy and specificity, especially for unknown cell types.

The paper shows pervasive transcription affects replication origin activity in budding yeast by pausing and terminating RNAPII transcription near origins.

This study shows that General Regulatory Factors like Rap1 suppress ectopic transcription initiation and maintain nucleosome positioning, ensuring transcription fidelity in yeast.

Sharq preprocesses single cell RNA-seq data from fastq files to gene expression tables, addressing amplification biases and providing quality control diagnostics.