Drice Challal

A bifunctional snoRNA with separable activities in guiding rRNA 2'-O-methylation and scaffolding gametogenesis effectors

The paper identifies a bifunctional snoRNA, snR107, that guides rRNA modification and scaffolds gametogenesis effectors in fission yeast.

A dual, catalytic role for the fission yeast Ccr4-Not complex in gene silencing and heterochromatin spreading

This study identifies the dual role of the fission yeast Ccr4-Not complex in gene silencing and heterochromatin spreading through RNA deadenylation and protein ubiquitinylation.

Sen1 is a key regulator of transcription-driven conflicts

The paper shows Sen1 resolves transcription-driven conflicts and maintains genomic stability by terminating non-coding transcription and resolving R-loops.

Xrn1 influence on gene transcription results from the combination of general effects on elongating RNA pol II and gene-specific chromatin configuration

This study investigates how Xrn1 affects transcription elongation in yeast by analyzing RNA polymerase II profiles and chromatin structure.

Opposing chromatin remodelers control transcription initiation frequency and start site selection

The paper investigates how opposing chromatin remodelers influence transcription initiation frequency and start site selection in budding yeast by analyzing their binding and nucleosome displacement activity.

General Regulatory Factors control the fidelity of transcription by restricting non-coding and ectopic initiation

This study shows that General Regulatory Factors like Rap1 suppress ectopic transcription initiation and maintain nucleosome positioning, ensuring transcription fidelity in yeast.