Author

Vladimir V. Shuvaev

University of PennsylvaniaORCID 0000-0003-2449-460XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Drew WeissmaniD· 2 shared Amie AlbertusiD· 1 shared Angela R. CorriganiD· 1 shared Anit ShahiD· 1 shared Aparajeeta MajumderiD· 1 shared Beverly H. KolleriD· 1 shared Carolann L. EspyiD· 1 shared David B FrankiD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersImmunology

Drew WeissmanORCID

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3 papers

Recent·Most cited

Cell BiologyCell ReportsPeer-reviewedSep 1, 2026

The Regulation of COX-2, ABCA1 and ABCG1 by the lncRNA PACERR links the inflammatory response and cholesterol homeostasis

Elizabeth J. Hennessy, Takae Tanosaki, Ronan Lordan…·Garret A. FitzGerald

This paper identifies PACERR as a lncRNA that regulates COX-2 and cholesterol transport genes, linking inflammation and cholesterol homeostasis through distinct mechanisms in response to HDL and LPS.

DOI 10.1016/j.celrep.2026.117934

humanexperimental assay

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ImmunologyScience ImmunologyPeer-reviewedMay 29, 2026

In vivo reprogramming of cytotoxic effector CD8+ T cells via fractalkine-conjugated mRNA-LNP

Angela R. Corrigan, Shin Foong Ngiow, Maura Statzu…·Michael R. Betts

This study shows fractalkine-conjugated mRNA-LNP can target and modify CD8+ T cells in vivo, enabling transient expression of proteins like IL-2 and CD62L.

1 citation

mouserat

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BioengineeringAdvanced SciencePeer-reviewedJan 20, 2026

Targeting DNA-LNPs to Endothelial Cells Improves Expression Magnitude, Duration, and Specificity

Nicolas Marzolini, Taylor V. Brysgel, Ryan J. Rahman…·Jacob Samuel Brenner

This study shows that targeting DNA-LNPs to endothelial cells enhances transgene expression magnitude, duration, and specificity in target organs.

6 citationstop 2%

mouseDNA methylation

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