Author

Nicolas Marzolini

University of PennsylvaniaORCID 0000-0002-0658-8664Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Aparajeeta MajumderiD· 2 shared Jacob Samuel BrenneriD· 2 shared Jacob W. MyersoniD· 2 shared Jichuan WuiD· 2 shared Liam S. ChaseiD· 2 shared Oscar Armando Marcos-ContrerasiD· 2 shared Taylor V. BrysgeliD· 2 shared Anit ShahiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersBioengineering

Aparajeeta MajumderORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Nanoparticle Albumin-Bound Paclitaxel Targets Pulmonary Neutrophils

Aparajeeta Majumder, Soomin Jeong, Marco Zamora, Nicolas Marzolini, Yufei Wang, Jia Nong, Taylor V. Brysgel, Priyal Patel, Michael H. Zaleski, Jichuan Wu, Collin T. Stabler, Liam S. Chase, Zhicheng Wang, Edward E. Morrisey, Vladimir Muzykantov, , Jacob W. Myerson

This paper identifies pulmonary neutrophils as the primary target of Abraxane in lung cancer and shows that its efficacy depends on complement pathway-mediated lung uptake.

bioRxiv · Sep 28, 2026 · PreprintBioengineering

Targeting DNA-LNPs to Endothelial Cells Improves Expression Magnitude, Duration, and Specificity

Nicolas Marzolini, Taylor V. Brysgel, Ryan J. Rahman, Eno‐Obong Essien, Saw Y. Nwe, Jichuan Wu, Aparajeeta Majumder, Manthan N. Patel, Sachchidanand Tiwari, Carolann L. Espy, Fengyi Dong, Sabrina A. Santos‐De León, Anit Shah, Vladimir V. Shuvaev, Elizabeth D. Hood, , Jacob Samuel Brenner

This study shows that targeting DNA-LNPs to endothelial cells enhances transgene expression magnitude, duration, and specificity in target organs.

Advanced Science · Jan 20, 2026Peer-reviewedBioengineering