Author
Parker Institute for Cancer ImmunotherapyORCID 0000-0002-5738-2834Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Kyungsoo Park, Juneil Jang, Shin Jeon…·Yeong Shin Yim
This study identifies brain-resident CD8+ T cells that regulate neuronal activity and behavior through interferon-gamma secretion, showing their role in maintaining brain homeostasis.
Angela R. Corrigan, Shin Foong Ngiow, Maura Statzu…·Michael R. Betts
This study shows fractalkine-conjugated mRNA-LNP can target and modify CD8+ T cells in vivo, enabling transient expression of proteins like IL-2 and CD62L.
Shin Foong Ngiow, Ryan P. O’Connell, Sasikanth Manne…·E. John Wherry
The paper shows that a drug holiday during PD-1 blockade improves reinvigoration of exhausted T cells by restoring progenitor cell function and reducing adaptive resistance.
Simone L. Park, Mark M. Painter, Sasikanth Manne…·E. John Wherry
The paper identifies TR-TEX cells as distinct from TRM cells, showing they have unique transcriptional regulation and respond differently to PD-1 inhibition.