Author

Mary Jo Ondrechen

Northeastern UniversityORCID 0000-0003-2456-4313Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Assay:imaging· 2 Organism:non-human primate· 2 Organism:rat· 2 Organism:human· 1

Frequent Co-Authors

Anna‐Liisa BrownelliD· 2 shared Dalena HuynhiD· 2 shared Gengyang YuaniD· 2 shared Georges El FakhriiD· 2 shared Hye Jin KangiD· 2 shared Julie E. PickettiD· 2 shared Maëva DhaynautiD· 2 shared Manish Kumar JainiD· 2 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersNeuroscience

Anna‐Liisa BrownellORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

NeuroscienceJournal of Medicinal ChemistryPeer-reviewedJul 8, 2022

Design, synthesis, and characterization of mG2P026 as a high contrast PET imaging ligand for metabotropic glutamate receptor 2

Gengyang Yuan, Maëva Dhaynaut, Nicolas J. Guehl…·Anna‐Liisa Brownell

The paper describes the synthesis and characterization of [18F]mG2P026 as a PET ligand for mGluR2, showing improved brain permeability and binding compared to existing compounds.

8 citations

ratnon-human primate

𝕏 PostBluesky

NeuroscienceJournal of Medicinal ChemistryPeer-reviewedJan 28, 2022

Synthesis and characterization of 5-(2-fluoro-4-pyridine-7-carboxamide as a PET imaging ligand for metabotropic glutamate receptor 2

Gengyang Yuan, Maëva Dhaynaut, Yu Lan…·Anna‐Liisa Brownell

The paper develops and characterizes [11C]13, a PET ligand for mGluR2, showing its brain distribution and response to mGluR2 NAMs in rats and nonhuman primates.

5 citations

ratnon-human primate

𝕏 PostBluesky

NeurosciencebioRxivPreprintJun 23, 2021

Protein crosslinking as a therapeutic strategy for SOD1-related ALS

Md Amin Hossain, Richa Sarin, Daniel P. Donnelly…·Jeffrey N. Agar

This paper demonstrates that a cyclic thiosulfinate cross-linker stabilizes SOD1 variants in vivo, showing efficacy and low toxicity for treating SOD1-related ALS.

2 citations

humanexperimental assay

𝕏 PostBluesky