Design, synthesis, and characterization of mG2P026 as a high contrast PET imaging ligand for metabotropic glutamate receptor 2
Gengyang Yuan, Maëva Dhaynaut, Nicolas J. Guehl, Sepideh Afshar, Dalena Huynh, Sung‐Hyun Moon, Suhasini M. Iyengar, Manish Kumar Jain, Julie E. Pickett, Hye Jin Kang, Mary Jo Ondrechen, Georges El Fakhri, Marc D. Normandin, Anna‐Liisa Brownell
The paper describes the synthesis and characterization of [18F]mG2P026 as a PET ligand for mGluR2, showing improved brain permeability and binding compared to existing compounds.
Journal of Medicinal Chemistry · Jul 8, 2022Peer-reviewedNeuroscience