Author

Chibueze Agwu

Washington University in St. LouisORCID 0000-0003-2458-1025Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Alyssa EricksoniD· 1 shared Azad BonniiD· 1 shared Harrison W. GabeliD· 1 shared Katheryn B. LeftoniD· 1 shared Ladan Abbasi· 1 shared Sabin A. NettlesiD· 1 shared Thomas PapouiniD· 1 shared Yoshiho IkeuchiiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperNeuroscience

Alyssa EricksonORCID

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1 paper

Recent·Most cited

NeuroscienceCell ReportsPeer-reviewedDec 1, 2023

MeCP2 Represses the Activity of Topoisomerase IIβ in Long Neuronal Genes

Sabin A. Nettles, Yoshiho Ikeuchi, Katheryn B. Lefton…·Harrison W. Gabel

This study identifies a functional interaction between MeCP2 and TOP2β in neurons, showing MeCP2 inhibits TOP2β activity at long genes, which may contribute to neurodevelopmental disorders.

13 citations

humanDNA methylation

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