Thomas Papouin

This study shows that astrocyte-specific deletion of Bmal1 disrupts circadian rhythms in perineuronal nets, synaptic plasticity, and learning behavior.

This study identifies astrocytes and D-serine/NMDAR signaling as key mediators of the cognitive benefits of α7nAChRs and their targeting therapeutics in mice.

This study shows that ventral striatal astrocytes influence reinforcement learning by modulating decision noisiness and reward-guided choice through calcium dynamics.

This study shows that norepinephrine modulates synapses via astrocytic adrenergic receptors and Ca2+ dynamics, independent of neuronal receptors.

STARDUST is a pipeline that analyzes astrocyte calcium dynamics by detecting and extracting discrete calcium signals from fluorescence recordings.

This study identifies a functional interaction between MeCP2 and TOP2β in neurons, showing MeCP2 inhibits TOP2β activity at long genes, which may contribute to neurodevelopmental disorders.

This study examines how different DNMT3A mutations cause varied behavioral, epigenetic, and transcriptional issues in neurodevelopmental disorders.

This study shows that DNMT3A mutations cause behavioral and epigenomic changes in mice, similar to human neurodevelopmental disorders, by disrupting non-CG DNA methylation.