Okihide Hikosaka

The paper shows that SNr and FEF encode different aspects of decision-making: SNr reflects ordinal rank, while FEF reflects categorical commitment, supporting a division of labor in neural circuits.

This study identifies three functionally distinct STN neuron populations in macaques during a value-based task, showing that two primarily encode stimulus value and precede GPe activity.

The paper identifies how value signals influence different neuron subtypes in the superior colliculus to modulate saccadic vigor during eye movements.

This study uses retrograde optogenetics in macaques to show that FEF outputs to the superior colliculus are diverse but predominantly motor-related, supporting a visuomotor convergence model.

This study investigates the role of the primate globus pallidus external segment in action initiation and suppression using single-unit recordings in macaques, identifying distinct neuronal clusters with facilitatory and inhibitory functions.

This study investigates how SNr neurons in macaques modulate activity to facilitate and suppress actions, showing that glutamatergic inputs are critical for suppression.

The paper shows that visual information propagates as a heterogeneous mixture of stochastic neural population signals across brain-wide regions in monkeys.

The paper investigates how periaqueductal gray (PAG) activity modulates reward-seeking behavior by suppressing escape responses and promoting persistence during disappointment.

The paper identifies neurons in the anterior striatum of macaques involved in proactive inhibition during a decision-making task.

The paper investigates how prefrontal cortex and basal ganglia represent value learning in macaques, finding that PFC signals value categories while SNr reflects value variability.

This study investigates the opposing roles of glutamatergic inputs to the GPe and SNr in basal ganglia function using behavioral tasks in monkeys.

The paper identifies a neuronal mechanism in the striatum tail that links social familiarity and object value, showing their shared encoding in face detection.

The paper shows that amygdala neurons regulate dopamine neurons via disinhibition in rewarding environments, linking environmental context to basal ganglia circuits.

This study uses quantitative susceptibility mapping (QSM) to better visualize subcortical structures in non-human primates, showing improved contrast-to-noise ratios and age-related changes.

This study shows that the central amygdala (CeA) controls saccades and gaze direction based on emotional and social contexts through inactivation and optogenetic stimulation in monkeys.

The paper uses fMRI in macaques to show that novelty and value coding segregate across functionally connected brain networks, with distinct patterns in ventral temporal, parietal, and TP networks.

The paper investigates how the indirect pathway of the caudate tail in monkeys controls rejection of bad objects during a saccade choice task.

The paper demonstrates that repeated reward experience enables macaques to efficiently search for high-value objects, with search times decreasing and accuracy increasing with longer training.