David A. Leopold

Immersive display systems for simulating natural vision

The paper develops hemispherical display systems for macaque visual neuroscience to study immersive and dynamic aspects of vision.

Targeted gene transfer into developmentally defined cell populations of the primate brain

This paper introduces a method for targeted gene transfer into specific cell populations of the fetal primate brain using ultrasound-guided viral injections.

Calcium-permeable AMPA receptors govern PV neuron feature selectivity

This study shows that calcium-permeable AMPA receptors (CP-AMPARs) in PV interneurons reduce their feature selectivity, and removing them increases selectivity in visual cortex and hippocampus.

Brain Charts for the Rhesus Macaque Lifespan

This study creates normative brain growth charts for rhesus macaques across their lifespan using MRI data, revealing developmental milestones and cross-species comparisons with humans.

Propagating cortical waves coordinate sensory encoding and memory retrieval in the human brain

The paper shows that human brain activity alternates between exteroceptive and interoceptive states through propagating fMRI waves, coordinating sensory encoding and memory retrieval.

Diffusion kurtosis MRI tracks gray matter myelin content in the primate cerebral cortex

This study shows that diffusion kurtosis MRI (MK) strongly correlates with myelin content in the primate cerebral cortex, offering a non-invasive method to assess gray matter myelination.

Intrinsic forebrain arousal dynamics governs sensory stimulus encoding

This study shows that intrinsic forebrain arousal dynamics during passive viewing influence visual stimulus encoding efficiency in the visual cortex.

Temporal continuity shapes visual responses of macaque face patch neurons

This study shows that disrupting temporal continuity in visual stimuli alters neural responses in macaque face patch neurons, suggesting that models based on randomized stimuli may not reflect natural visual processing.

Diffusion MRI Anisotropy in the Cerebral Cortex is Determined by Unmyelinated Tissue Features

This study shows that dMRI-FA in the cerebral cortex is primarily influenced by unmyelinated tissue features rather than myelinated axons.

Cascades of neuronal plasticity in the macaque visual cortex

The paper tracks neuronal adaptation in macaque visual cortex over weeks of exposure to novel faces, finding cell-specific time constants governed by testing days, not stimulus exposures.

Self-generated brain-wide spiking cascades govern replay dynamics in the hippocampus

The paper investigates how brain-wide spiking cascades during rest relate to hippocampal replay sequences in mice, finding that replay events are linked to specific types of cascades.

Parallel functional subnetworks embedded in the macaque face patch system

The paper identifies parallel functional subnetworks of face-selective neurons in macaques during natural video viewing.

Single neuron firing cascades underlie global spontaneous brain events

The paper identifies large-scale neuronal firing cascades in the mouse brain during rest, showing they are synchronized with global events and linked to arousal and sensory processing.

The road not taken: disconnection of a human-unique cortical pathway in schizophrenia and its effects on naturalistic social cognition

The paper examines connectivity deficits in schizophrenia, showing disrupted pathways in social cognition networks and their impact on brain function.

Visualization of subcortical structures in non-human primates in vivo by Quantitative Susceptibility Mapping at 3T MRI

This study uses quantitative susceptibility mapping (QSM) to better visualize subcortical structures in non-human primates, showing improved contrast-to-noise ratios and age-related changes.

Brain activity fluctuations propagate as waves traversing the cortical hierarchy

This study identifies directionally constrained activity waves in human and monkey brain data that align with cortical hierarchy and subcortical structures.

Object novelty and value coding segregate across functionally connected brain networks

The paper uses fMRI in macaques to show that novelty and value coding segregate across functionally connected brain networks, with distinct patterns in ventral temporal, parietal, and TP networks.

Midbrain activity supports high-level visual properties in primate temporal cortex

The paper shows that the superior colliculus influences high-level visual processing in primate temporal cortex by affecting attention and object selectivity.

Delayed suppression normalizes face identity responses in the primate brain

The paper shows that delayed suppression in primate face patches enhances sensitivity to facial identity features through predictive normalization.

Failure to engage the TPJ-pSTS during naturalistic scene processing in schizophrenia

This study uses fMRI to show reduced TPJ-pSTS engagement during naturalistic scene processing in schizophrenia, linking it to impaired social cognition and visual scanning.

Spatial neglect is causally linked to an attention-related area in macaque temporal cortex

The paper identifies a mid-STS region in macaques as causally linked to spatial neglect through fMRI and inactivation experiments.

Morphometric Similarity Networks Detect Microscale Cortical Organisation And Predict Inter-Individual Cognitive Variation

The paper introduces morphometric similarity networks to map cortical organization and shows they predict cognitive variation across individuals.

An open resource for nonhuman primate imaging

The paper introduces PRIME-DE, an open resource for non-human primate MRI data, aggregating 13 datasets from 11 sites across 98 macaques.

A population MRI brain template and analysis tools for the macaque

The paper presents a high-resolution MRI template and analysis tools for macaque brains, enabling standardized processing and comparison across subjects and studies.