Rhys N. Colson

This study shows that NHL-2's RNA-binding activity is essential for miRNA-mediated gene regulation in C. elegans, linking it to translational repression and miRISC complex function.

The paper determines the X-ray crystal structure of SARS-CoV-2 Nsp9 in apo and peptide-bound forms, revealing structural conservation and a peptide-binding site near the dimer interface.

This study identifies NHL-2 as a co-factor in C. elegans germline 22G-RNA pathways and shows it regulates gene expression through RNA binding and stability.