Julie M. Claycomb

The paper uses TurboID proximity labeling to map protein interaction networks of germline Argonautes in C. elegans, revealing distinct interactions and potential nuclear roles for some proteins.

This study shows that NHL-2's RNA-binding activity is essential for miRNA-mediated gene regulation in C. elegans, linking it to translational repression and miRISC complex function.

The paper systematically analyzes all 19 AGO proteins in C. elegans to uncover gene regulatory networks and novel phenotypes associated with their loss.

The paper identifies two CSR-1 isoforms in C. elegans and shows they have distinct roles in fertility and immunity.

The paper shows that P granules in C. elegans germ cells prevent RNA interference genes from being silenced by piRNAs, maintaining their expression.

The paper shows that transgenerational small RNA inheritance in C. elegans can occur independently of germ granules in some mutants, but depends on ancestral germ granule function and HRDE-1.

The paper shows that genome structure influences modular transcriptome responses to genetic and environmental conditions in C. briggsae.

The paper identifies an Argonaute protein secreted by a nematode that mediates the release of specific siRNAs into the host environment.

This study identifies NHL-2 as a co-factor in C. elegans germline 22G-RNA pathways and shows it regulates gene expression through RNA binding and stability.

This study identifies the Aquarius/EMB-4 helicase as essential for initiating small RNA-induced co-transcriptional gene silencing in C. elegans by facilitating HRDE-1 complex engagement with nascent transcripts.