The human branchpoint-interacting stem loop sequence and structure regulates U2 snRNA expression, branchpoint recognition, and transcriptome.
Meredith Stevers, Sol J. Katzman, Melissa S. Jurica
This study investigates how the branchpoint-interacting stem loop (BSL) structure in U2 snRNA affects splicing efficiency and gene expression by altering branchpoint recognition and U2 snRNP biogenesis.