Pearl J. Quijada

This study uses single-cell RNA sequencing to profile epicardial cell states during myocardial infarction, identifying dynamic gene programs and cell populations involved in repair and regeneration.

This study shows FZD2 inhibits YAP and prevents adult murine cardiomyocytes from reentering the cell cycle, and its deletion improves heart function and reduces scarring after myocardial infarction.