Nazanin Ahmadi Daryakenari

This paper develops a multiscale modeling framework to study macrophage-mediated RBC clearance in sickle cell disease and Gaucher disease, revealing altered signaling and biophysical mechanisms.

This paper develops a computational platform to evaluate anti-sickling agents by integrating PK/PD models with RBC sickling kinetics, demonstrating its utility in predicting therapeutic efficacy and noncompliance outcomes for existing and potential drugs.