Author

Shane P. Herbert

University of ManchesterORCID 0000-0003-2517-1845Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:zebrafish· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Guilherme CostaiD· 2 shared Joshua J BradburyiD· 2 shared Katie BentleyiD· 2 shared Raphaël ThuretiD· 2 shared Bruno LarrivéeiD· 1 shared Cecilia SahlgreniD· 1 shared Christopher S. CheniD· 1 shared Donna J. PageiD· 1 shared

Activity by Year

2019-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCell Biology

Guilherme CostaORCID

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4 papers

Recent·Most cited

Developmental BiologyDevelopmental CellPeer-reviewedFeb 5, 2026

Bmp9 regulates Notch signaling and the temporal dynamics of angiogenesis via Lunatic Fringe

Tommaso Ristori, Raphaël Thuret, Erika Hooker…·Katie Bentley

This study shows Bmp9 upregulates Lunatic Fringe in endothelial cells, enhancing Notch signaling and regulating angiogenesis dynamics.

9 citations

mousebulk RNA-seq

𝕏 PostBluesky

Cell BiologyNature CommunicationsPeer-reviewedJul 31, 2025

mRNA trafficking directs cell-size-scaling of mitochondria distribution and function

Joshua J Bradbury, Georgia E. Hulmes, Ranjith Viswanathan…·Shane P. Herbert

The paper shows that mRNA trafficking directs cell-size-dependent mitochondria distribution and function through a 3UTR motif that regulates TRAK2 mRNA localization.

5 citations

metabolomicsexperimental assay

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Developmental BiologybioRxivPreprintAug 11, 2019

mRNA compartmentalisation spatially orients tissue morphogenesis

Guilherme Costa, Joshua J Bradbury, Nawseen Tarannum, Shane P. Herbert

The paper shows mRNA polarisation orients cell polarity and tissue movement by directing RAB13 function to specific subcellular sites in zebrafish.

2 citations

zebrafishbulk RNA-seq

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Developmental BiologyCell ReportsPeer-reviewedJun 1, 2019

Positive-feedback defines the timing and robustness of angiogenesis

Donna J. Page, Raphaël Thuret, Lakshmi Venkatraman…·Shane P. Herbert

The paper identifies a positive-feedback mechanism involving Tm4sf18 that accelerates and stabilizes endothelial cell decision-making during angiogenesis.

35 citations

zebrafishstatistical model

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