Vignesh M. P. Babu

This study shows TDP-43 amyloid forms only when its C-terminal domain arrests in soluble clusters, and this process can be inhibited by co-expressing an oligomeric binder.

This study uses stereochemistry and genetics to distinguish the mechanisms of action of NCR247 on bacterial cells, revealing distinct effects in the periplasm and cytoplasm.

The paper introduces a tool to study how modifier proteins affect the phase behavior of query proteins through controlled interaction modulation.