Author

Dagan Wells

John Radcliffe HospitalORCID 0000-0003-2633-9099Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Afshan McCarthyiD· 1 shared Antonio CapalboiD· 1 shared António PelliceriD· 1 shared Antonio RequenaiD· 1 shared Carlos Marin Vallejo· 1 shared Chaim JalasiD· 1 shared Christian Simon OttoliniiD· 1 shared D BabariyaiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperDevelopmental Biology

Afshan McCarthyORCID

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2 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintJun 23, 2025

PGT-A Mosaicism Reporting Lacks Clinical Predictive Value: Evidence from a Multisite, Double-Blinded Study with Independent Validation Across 15,315 Single-Embryo Transfers

P. Gill, Xin Tao, Yiping Zhan…·Antonio Capalbo

This study shows that reporting mosaicism in PGT-A based on intermediate copy number (ICN) does not improve clinical outcomes in embryo selection.

DOI 10.1101/2025.06.23.25329758

humanstatistical model

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Developmental BiologyProceedings of the National Academy of SciencesPeer-reviewedApr 9, 2021

Frequent loss-of-heterozygosity in CRISPR-Cas9-edited early human embryos

Gregorio Alanis‐Lobato, Jasmin Zohren, Afshan McCarthy…·Kathy K. Niakan

The paper analyzes single-cell genomics and transcriptomics data from CRISPR-Cas9-edited human embryos to assess unintended editing outcomes and loss-of-heterozygosity.

233 citationstop 1%

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