Lingxia Qiao

This study uses a particle-based model to simulate flat clathrin lattice dynamics, showing how AP-2, clathrin binding, and diffusion affect their formation and response to EGF stimulation.

The paper develops a computational model to simulate how different exercise regimes affect mitochondrial fission and fusion dynamics in skeletal muscle.

The paper develops computational models of the Ca2+/cAMP pathway and AKAP/AC nanodomains, predicting incoherent feedforward loop behavior in Ca2+/cAMP oscillations.

The paper identifies network design principles for robust oscillatory behaviors in transcriptional regulatory networks under biological noise.

This paper investigates design principles for dose-response alignment in signaling motifs with negative feedback loops, showing how kinetic parameters and activation levels affect performance.

The paper identifies a GTPase circuit that enables secretion-coupled cellular autonomy in cancer cells through feedback loops and dose response alignment of growth factor sensing and secretion.

The paper develops a mathematical model to explain the formation and function of bivalent chromatin by analyzing the dynamics of H3K4me3 and H3K27me3 modifications.