Cancer BiologybioRxivPreprint
METTL1 gene dosage and catalytic activity define a targetable vulnerability in pediatric cancers
Pei Yan Liu, Steven He, Olesya O. Panasenko…·Paul G. Ekert
This study identifies METTL1 gene dosage and catalytic activity as therapeutic targets in pediatric cancers, showing that inhibiting METTL1 synergizes with BCL-xL inhibitors.
DOI 10.64898/2026.10.20.760582