GeneticsbioRxivPreprint
Repurposing the TIGR-Tas system for programmable transcription activation
Yetong Sang, Li Xu, Nga Man Wong…·Zehua Bao
This paper repurposes the TIGR-Tas system for gene activation, achieving robust and specific transcriptional activation of human genes with a compact system potentially independent of PAMs.
DOI 10.64898/2026.07.30.739400