Author

Chaitanya Naimesh Parikh

University of Massachusetts Chan Medical SchoolORCID 0000-0003-2728-3998Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1 Assay:multiome· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Boyang MaiD· 2 shared Marcus A. RuscettiiD· 2 shared Wen XueiD· 2 shared Youwei QiaoiD· 2 shared Brian C. Lewis· 1 shared Calvin Johnson· 1 shared Griffin I. KaneiD· 1 shared Hadiya K. GiwaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Boyang MaORCID

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2 papers

Recent·Most cited

Cancer BiologyNature CommunicationsPeer-reviewedJun 19, 2026

Multiplexed cytokine and antigen mRNA administration generates durable anti-tumor immunity against pancreatic cancer

Chaitanya Naimesh Parikh, Kelly D. DeMarco, Nikita Bhalerao…·Marcus A. Ruscetti

This study shows that delivering multiple cytokine and antigen mRNAs via nanoparticles can generate strong anti-tumor immunity against pancreatic cancer in mice.

2 citations

mousemultiome

𝕏 PostBluesky

Cancer BiologyAdvanced SciencePeer-reviewedDec 3, 2025

KRAS withdrawal in Cholangiocarcinoma leads to immune infiltration and tumor regression

Youwei Qiao, Matthew F. Yee, Chaitanya Naimesh Parikh…·Wen Xue

This study shows that removing KRASG12D in a mouse model of cholangiocarcinoma leads to tumor regression through immune infiltration and activation of CD8+ T cells.

1 citation

mousespatial transcriptomics

𝕏 PostBluesky