Christopher P. Ptak

The paper identifies nucleotide-specific interactions of Rab GTPases using yeast 2-hybrid and high-throughput sequencing, revealing new effector interactions and a novel Rab-binding domain.

This study identifies the molecular interaction between PMP22 and MPZ through their transmembrane domains and shows how disrupting this interaction causes a loss-of-function phenotype in hereditary neuropathy.

The paper investigates the structural context of homomeric interactions in the Ig domain of MPZ and their relation to CMT disease phenotypes using NMR and SAXS analysis.

The paper identifies differences in the tau interactome between fetal and Alzheimer disease brains, showing isoform-dependent interactions with 14-3-3 proteins.