Yuanyi Feng

The paper shows that abrogating filamin in mouse models of periventricular heterotopia increases neocortical neuron generation in the V-SVZ through oxidative metabolism and vascularization.

This study shows that neuronal DNA damage leads to senescence, which causes cerebrovascular lesions and neurodegeneration through inflammatory and vascular pathways.

This study identifies NDE1's role in heterochromatin compaction and stability in neocortical neurons, linking its dysfunction to neurodevelopmental and neuropsychiatric disorders.

This study shows Brap loss leads to H2A ubiquitination, causing aging hallmarks and neurodegeneration in mice, with similar findings in Alzheimer's human brain tissue.