Edwin S. Monuki

The paper examines age-related accumulation of Biondi bodies in human choroid plexus epithelial cells, finding nonlinear increases in prevalence and load, and suggesting prion-like spread mechanisms.

The paper investigates the association between Alzheimer's disease and Biondi body amyloid in hippocampal-associated choroid plexus epithelial cells and ependymal cells, finding a near-significant increase in BB-containing CPECs and a significant increase in BB-like amyloid in ependymal cells in AD.

This study identifies age and adiposity-related lipid droplet accumulation in human choroid plexus epithelial cells, with associations with BMI, sex, and Alzheimer's Disease.

The paper describes a multi-institutional program for collecting neurotypical human brains to support multiomic brain cell atlas studies, highlighting challenges and opportunities for donor recruitment.

This study shows that human neural stem cells transplanted into Huntington's disease mouse models improve behavior, reduce mutant Huntingtin, and integrate functionally into the host brain.

This study shows Brap loss leads to H2A ubiquitination, causing aging hallmarks and neurodegeneration in mice, with similar findings in Alzheimer's human brain tissue.

The paper shows that cooperative transcription factors Lhx2 and Ebf specify olfactory receptor enhancers, enabling singular OR expression through interchromosomal interactions.