Pieta K. Mattila

This study identifies a distal super-enhancer near CCNG2 that drives aberrant CXCL13 expression in cancer cells, leading to growth promotion and p53 dysregulation via the CXCR5-CXCL13 axis.

The paper introduces GlycoAvatars, bead-coated membrane models, to study glycan-mediated interactions between cancer and immune cells, identifying molecular nodes involved in immune synapses.

This study shows that B cell-derived extracellular vesicles from activated B cells stimulate lytic gene expression of oncogenic herpesviruses.

This study uses dynamic micropatterning to analyze B cell receptor signaling and immune synapse formation, revealing distinct spatial distributions of activated proteins and actin-based protrusion repurposing.

AutoCoEv predicts inter-protein co-evolution from large datasets, identifying novel interactions and functional clusters among 324 B lymphocyte lipid raft proteins.

ZeroCostDL4Mic provides a platform to use deep learning in microscopy, enabling tasks like segmentation and denoising through Google Colab.