Author

Erica M. Orsini

Cleveland ClinicORCID 0000-0003-2805-4783Unclaimed ORCID profile · follow to get notified of new preprints

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Adam M. BoultoniD· 1 shared Akash AhujaiD· 1 shared Alyson Brown· 1 shared Amanda Reinhardt· 1 shared Amy Houghton AttawayiD· 1 shared Bishnu Datt PantiD· 1 shared Caitlin M. Snyder· 1 shared Haley Ricci· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Adam M. BoultonORCID

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1 paper

Recent·Most cited

ImmunologybioRxivPreprintNov 6, 2025

NF-kB-Dependent Transcriptional Regulation of Piezo1 Mediates Bacterial Clearance on Stiffened Lung

Erica M. Orsini, Adam M. Boulton, Susamma Abraham…·Rachel Greenberg Scheraga

This study shows that NF-kB-dependent transcription of Piezo1 in macrophages enhances bacterial clearance during pneumonia by promoting lysosome biogenesis and stiffness-dependent phagolysosome maturation.

DOI 10.1101/2025.11.06.687026

mousebulk RNA-seq

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