Author

Mike van Heumen

Maastricht University Medical CentreORCID 0000-0003-2807-5023Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

Ann HoebeniD· 1 shared Jolanda A. F. Piepers· 1 shared Kim Rosalie KampeniD· 1 shared Linde Hoosemans· 1 shared Marc VooijsiD· 1 shared Sander S. RenseniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperCancer Biology

Ann HoebenORCID

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintOct 28, 2025

Adaptive Kinase Signaling Enables Escape from Small-Molecule Inhibition in Glioblastoma

Mike van Heumen, Linde Hoosemans, Jolanda A. F. Piepers…·Marc Vooijs

This study identifies compensatory pathway activation as a mechanism of resistance to single-agent small-molecule inhibitors in glioblastoma and shows that combination therapy can overcome this resistance.

DOI 10.1101/2025.10.28.684838

humanorganoid / primary culture

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