Guilherme Horta

This study shows that deleting Shank3 in glutamatergic neurons of the anterior insular cortex causes autism-like behaviors and circuit dysfunction in mice.

This study shows that restoring CB1R in the anterior insular cortex of CB1R-deficient mice normalizes social novelty discrimination and reduces anxiety-like behavior without affecting other behaviors.

This study identifies NECAB2's role in an endosomal pathway for mitochondrial stress response and repair in striatal synapses, linking its loss to synaptic loss and behavioral deficits.