Iñigo Ruı́z de Azúa

Selective Shank3 Deletion in Glutamatergic Neurons of the Anterior Insular Cortex Induces Autism-Related Behavior and Circuit Dysfunction

This study shows that deleting Shank3 in glutamatergic neurons of the anterior insular cortex causes autism-like behaviors and circuit dysfunction in mice.

Anterior insular CB1 receptor signaling selectively regulates social novelty and anxiety-related behaviors

This study shows that restoring CB1R in the anterior insular cortex of CB1R-deficient mice normalizes social novelty discrimination and reduces anxiety-like behavior without affecting other behaviors.