Author

Danilo Faccenda

University of HertfordshireORCID 0000-0003-2827-2529Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Michelangelo CampanellaiD· 2 shared Aarti SinghiD· 1 shared Andrey A. YurchenkoiD· 1 shared Claudia De VitisiD· 1 shared Daniela StrobbeiD· 1 shared Dong Xia· 1 shared Eduardo Cremonese Filippi‐ChielaiD· 1 shared Elena Romano· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCell Biology

Michelangelo CampanellaORCID

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2 papers

Recent·Most cited

Cell BiologyPharmacological ResearchPeer-reviewedFeb 19, 2026

Mitochondria drive microglial NRLP3 inflammasome activation via TSPO

Aarti Singh, Manuel Rigon, Tong Guo…·Michelangelo Campanella

This study shows TSPO on mitochondria promotes microglial inflammasome activation by stabilizing NLR proteins, inhibiting mitophagy, and enhancing pro-inflammatory gene expression, leading to excitotoxicity.

6 citationstop 1%

mouseexperimental assay

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Cancer BiologybioRxivPreprintAug 27, 2024

Mitochondrial sites of contact with the nucleus aid in chemotherapy evasion of glioblastoma cells

Daniela Strobbe, Mardja Bueno, Claudia De Vitis…·Michelangelo Campanella

This study identifies TSPO-mediated mitochondrial-nuclear contacts as a mechanism enabling glioblastoma cells to evade TMZ chemotherapy, showing that modulating TSPO restores chemosensitivity.

2 citations

humanproteomics

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