Joshua K. Thackray

The paper develops a closed-loop optogenetic system using DeepLabCut-Live to manipulate sensory neuron activity during specific phases of locomotion in mice, revealing context-specific behavioral responses.

This study investigates how transplanted neural progenitor cell-derived neurons integrate into spinal cord locomotor circuits and their functional impact on motor recovery after injury.

This study identifies the role of the gracile nucleus in mediating tactile sensitivity and mechanical allodynia during neuropathic pain in mice.

This study shows treadmill training enhances corticospinal tract rewiring and improves motor recovery in SCI mice, with motivation influencing specific kinematic outcomes.

The paper generates mouse models with human mutations in TD genes, showing sensorimotor and reward learning phenotypes, dopamine changes, and sex-specific effects.

This study shows that Yoda1, a Piezo1 agonist, reduces intracranial pressure and improves CSF flow and meningeal lymphatic function in craniosynostosis and aged mice.

This study uses motion sequencing to analyze behavioral syllables after spinal cord injury, revealing recovery patterns shaped by injury severity and individual differences.

This study identifies glycinergic inhibitory neurons in the spinal cord deep dorsal horn that integrate sensory inputs and modulate motor output during locomotion.

This study shows a CELSR3 mutation linked to Tourette disorder alters dendritic patterning and excitability of cholinergic interneurons in mice without overt behavioral symptoms.

The paper maps behavioral signatures of inflammatory pain and its relief in mice using computational tools and identifies that a common anti-inflammatory drug does not fully restore pre-injury behavior.

This study identifies SirT7's dual role as a deacetylase and mADPRT enzyme, showing its regulation of glucose starvation response via interaction with macroH2A1.1.