Victoria E. Abraira

This study shows that Sall3 is essential for forming GABApre synapses on Ia afferents, and its loss disrupts motor behavior by impairing presynaptic inhibition.

This study identifies spinal oxytocin circuits as a conserved mechanism through which affiliative touch reduces pain and enhances well-being in mice and humans.

The paper introduces an automated device for delivering mechanical stimuli to mice, enabling remote testing and integration with brain recordings to study pain mechanisms.

This study identifies time-dependent changes in corticostriatal circuits and movement patterns in a chronic pain model, highlighting a critical 3-week transition phase for therapeutic intervention.

The paper develops a closed-loop optogenetic system using DeepLabCut-Live to manipulate sensory neuron activity during specific phases of locomotion in mice, revealing context-specific behavioral responses.

This study investigates how transplanted neural progenitor cell-derived neurons integrate into spinal cord locomotor circuits and their functional impact on motor recovery after injury.

This study identifies the role of the gracile nucleus in mediating tactile sensitivity and mechanical allodynia during neuropathic pain in mice.

This study shows treadmill training enhances corticospinal tract rewiring and improves motor recovery in SCI mice, with motivation influencing specific kinematic outcomes.

The paper investigates differences in subcellular anatomical distribution of M1 and S1 cortical inputs to SPNs and FSIs in the DLS, finding SPNs receive more M1 inputs and show input clustering.

This study uses motion sequencing to analyze behavioral syllables after spinal cord injury, revealing recovery patterns shaped by injury severity and individual differences.

This study identifies glycinergic inhibitory neurons in the spinal cord deep dorsal horn that integrate sensory inputs and modulate motor output during locomotion.

This paper introduces a new Hoxb8FlpO mouse line and intersectional genetics-viral strategy to target and manipulate developmentally defined adult spinal circuits.

The paper identifies Mrgprb4-lineage neurons as critical for sexual receptivity and dopaminergic reward from social touch in mice.

The paper maps behavioral signatures of inflammatory pain and its relief in mice using computational tools and identifies that a common anti-inflammatory drug does not fully restore pre-injury behavior.