Author
University at Buffalo, State University of New YorkORCID 0000-0003-2839-848XUnclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Bruce Nmezi, Guillermo Rodríguez Bey, Talia DeFrancesco Oranburg…·Quasar Saleem Padiath
The paper identifies a silencer element lost in ADLD patients that specifically targets oligodendrocyte overexpression of LMNB1, linking it to disease pathogenesis.
Jung-Mi Lee, Hunmin Jung, Bruno de Paula Machado Pasqua…·Hyuk-Jae Edward Kwon
This study shows that MLL4 is critical for midpalatal suture development and palate growth, with loss of MLL4 causing hypoplasia, widened suture, and disrupted cartilage development.
Kaiyu Jiang, Tao Liu, Susan Kales…·James N. Jarvis
This paper identifies causal SNPs and their target genes in JIA risk haplotypes using MPRA and CRISPRi, finding 84 SNPs that alter gene expression and regulate multiple genes in TRAF1 and LNPEP/ERAP2 loci.
James N. Jarvis, Kaiyu Jiang, Yungki Park…·Tao Liu
The paper identifies an intronic enhancer in the IL2RA gene that is functionally attenuated by JIA-associated genetic variants.