Gen Zheng

This study identifies an enhancer of Ctnnb1 that regulates Wnt signaling dosage, maintaining intestinal homeostasis and suppressing colorectal cancer.

The paper develops a 3D morphometric analysis pipeline for cell nuclei and nucleoli, achieving high classification accuracy in prostate cancer and fibroblast cells.

The paper introduces a 3D cell nuclear morphology dataset and evaluates classification algorithms using voxel-based morphometric measures.

The paper observes rotational 3D mechanogenomic Turing patterns in Caco-2 cells during differentiation, suggesting a link between actomyosin dynamics and gene morphogen-driven morphogenesis.