Sophie Jarriault

The paper identifies lin-15A as a Licenser that facilitates transdifferentiation by antagonizing identity safeguarding mechanisms in C. elegans.

This study compares cell-cycle gene expression dynamics and mRNA kinetics across mouse and human pluripotent systems, revealing species-specific differences in transcriptional complexity and oscillatory control.

The paper investigates the role of Notch signaling in natural transdifferentiation in C. elegans, showing it can both promote and block the process depending on timing.

The paper investigates a natural transdifferentiation event in C. elegans, showing that Wnt signaling and reprogramming factors work together to erase rectal identity and establish neuronal identity during cell division.

The paper introduces RAPID, a method to determine tissue-specific transcriptional footprints in C. elegans without cell sorting, and validates it by identifying novel transcriptional profiles in rare cell types.