Author

Jian‐Wen Huang

Hangzhou Normal UniversityORCID 0000-0003-2870-7780Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Chun‐Chi CheniD· 2 shared Rey‐Ting GuoiD· 2 shared Beibei LiuiD· 1 shared Caihong WangiD· 1 shared Deyi FengiD· 1 shared Hao LiiD· 1 shared J. LiuiD· 1 shared Jian MiniD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersMolecular Biology

Chun‐Chi ChenORCID

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2 papers

Recent·Most cited

Molecular BiologyACS CatalysisPeer-reviewedDec 5, 2025

Enabling regiospecific di-halogenation in one-pot reactions using an engineered single-component flavin-dependent tryptophan halogenase

Hao Li, Jian‐Wen Huang, Si Dai…·Rey‐Ting Guo

The paper engineers a single-component flavin-dependent tryptophan halogenase to enable regiospecific mono- and di-halogenation of tryptophan in one-pot reactions.

1 citation

experimental assay

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Molecular BiologyACS CatalysisPeer-reviewedAug 20, 2024

Structure of Geobacillus stearothermophilus Cas9: insights into the catalytic process and thermostability of CRISPR-Cas9

Panpan Shen, Lilan Zhang, Beibei Liu…·Rey‐Ting Guo

This study reports the cryo-EM structures of Geobacillus stearothermophilus Cas9 complexed with sgRNA and target DNA, revealing the catalytic mechanism and thermal stability features.

10 citations

bacteria (other)protein structure

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