Enabling regiospecific di-halogenation in one-pot reactions using an engineered single-component flavin-dependent tryptophan halogenase
Hao Li, Jian‐Wen Huang, Si Dai…·Rey‐Ting Guo
The paper engineers a single-component flavin-dependent tryptophan halogenase to enable regiospecific mono- and di-halogenation of tryptophan in one-pot reactions.