José Luis Cabrera-Alarcón

The paper shows that modifying ionic interactions with phospholipids prevents hypoxic adaptation by preserving inner mitochondrial membrane fluidity and CoQ transfer.

This study shows mitochondrial haplogroups affect tumour growth and anti-tumour immunity through mitochondrial ROS and PD-1 signalling in mouse models.

This study evaluates using locus variability, measured by Shannon entropy from variant allele frequencies, to predict pathogenic SNVs in mitochondrial and splice-site regions, showing strong performance compared to existing tools.

The paper introduces FCS and FCSMt, two scores for predicting pathogenic variants in nuclear and mitochondrial DNA, achieving high AUC values in validation datasets.

The paper introduces two variant pathogenicity prediction models, VSRFM and VSRFM-s, which incorporate splicing information and allele frequency to improve prediction accuracy.