Author

Uzi Gileadi

University of OxfordORCID 0000-0001-7348-9204Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Immunology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Vincenzo CerundoloiD· 2 shared Ana Victoria Lechuga‐ViecoiD· 1 shared Anagha Yogam Krishnan· 1 shared Audrey GérardiD· 1 shared David J. H. F. KnappiD· 1 shared David SanchoiD· 1 shared Edward W. RobertsiD· 1 shared Gennaro Prota· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersImmunology

Vincenzo CerundoloORCID

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3 papers

Recent·Most cited

Mitochondrial genetics defines anti-tumour immunity through mitochondrial ROS and PD-1 signalling

Gennaro Prota, Raquel Justo‐Méndez, Uzi Gileadi, Macarena De Andrés-Laguillo, José Luis Cabrera-Alarcón, María del Mar Muñoz-Hernández, Valeria Lupi, Sofía C Khouili, Raquel Martínez-De-Mena, Juan Pellico, Rui Benedito, Jesús Ruíz-Cabello, David Sancho, Jose Antonio Enríquez, Ana Victoria Lechuga‐Vieco

This study shows mitochondrial haplogroups affect tumour growth and anti-tumour immunity through mitochondrial ROS and PD-1 signalling in mouse models.

bioRxiv · Sep 18, 2026 · PreprintCancer Biology

IFNgamma-dependent remodelling of the myeloid landscape underlies control of IFNgamma-insensitive tumours

Vivian Wing Chong Lau, Gracie J. Mead, Zofia Varyova, Julie M. Mazet, Anagha Yogam Krishnan, Edward W. Roberts, Gennaro Prota, Uzi Gileadi, Kim S. Midwood, Vincenzo Cerundolo, Audrey Gérard

The paper shows that IFN-gamma-insensitive tumours can still be controlled by immune responses, with IFN-gamma driving myeloid cell remodelling that enhances anti-tumour immunity.

Nature Communications · Jan 2, 2025Peer-reviewedImmunology

Precise tuning of gene expression output levels in mammalian cells

Yale S. Michaels, Mike Bogetofte Barnkob, Hector Barbosa, Toni A. Baeumler, Mary Kay Thompson, Violaine André, Huw Colin‐York, Marco Fritzsche, Uzi Gileadi, Hilary M. Sheppard, David J. H. F. Knapp, Thomas A. Milne, Vincenzo Cerundolo, Tudor A. Fulga

This paper introduces miSFITs, synthetic microRNA response elements that allow precise control of gene expression levels in mammalian cells, showing their utility in modulating antigen expression in a mouse melanoma model.

Nature Communications · Feb 18, 2019Peer-reviewedSynthetic Biology