Author

Jean‐Philippe Richard

Johns Hopkins UniversityORCID 0000-0003-2890-2316Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Arens TagaiD· 3 shared Nicholas John MaragakisiD· 3 shared Jessica JosephiD· 2 shared Norman J. HaugheyiD· 2 shared Raha Maryam DastgheybiD· 2 shared Sarah K. GrossiD· 2 shared Aayush PokhareliD· 1 shared Akshata A. Almad· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersNeuroscience

Arens TagaORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

NeuroscienceMolecular NeurodegenerationPeer-reviewedJan 10, 2022

Edaravone activates the GDNF/RET neurotrophic signaling pathway and protects mRNA-induced motor neurons from iPS cells.

Qian Li, Yi Feng, Yingchao Xue…·Mingyao Ying

This paper shows edaravone protects mRNA-induced motor neurons from neurotoxicity by activating the GDNF/RET signaling pathway and can replace neurotrophic factors for neuron survival.

43 citationstop 4%

humanbulk RNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintMar 14, 2020

Connexin 43 hemichannels mediate spatial and temporal disease spread in ALS

Akshata A. Almad, Arens Taga, Jessica Joseph…·Nicholas John Maragakis

This study shows that Cx43 hemichannels in astrocytes contribute to ALS progression and that blocking them can protect neurons and improve survival in ALS models.

3 citations

mousehuman

𝕏 PostBluesky

NeuroscienceStem Cells Translational MedicinePeer-reviewedOct 21, 2019

Role of human induced pluripotent stem cell-derived spinal cord astrocytes in the functional maturation of motor neurons in a multielectrode array system

Arens Taga, Raha Maryam Dastgheyb, Christa Whelan Habela…·Nicholas John Maragakis

This paper develops a co-culture method for human iPSC-derived astrocytes and motor neurons in MEA systems, showing bidirectional maturation effects.

48 citations

humanbulk RNA-seq

𝕏 PostBluesky