Author

Jessica Joseph

Johns Hopkins UniversityORCID 0000-0002-0175-6809Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Organism:mouse· 1

Frequent Co-Authors

Arens TagaiD· 2 shared Jean‐Philippe RichardiD· 2 shared Nicholas John MaragakisiD· 2 shared Norman J. HaugheyiD· 2 shared Raha Maryam DastgheybiD· 2 shared Sarah K. GrossiD· 2 shared Aayush PokhareliD· 1 shared Akshata A. Almad· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersNeuroscience

Arens TagaORCID

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2 papers

Recent·Most cited

Connexin 43 hemichannels mediate spatial and temporal disease spread in ALS

Akshata A. Almad, Arens Taga, Jessica Joseph, Connor Welsh, Aneesh G. Patankar, Sarah K. Gross, Jean‐Philippe Richard, Aayush Pokharel, Mauricio A. Lillo, Raha Maryam Dastgheyb, Kevin C. Eggan, Norman J. Haughey, Jorge E. Contreras, Nicholas John Maragakis

This study shows that Cx43 hemichannels in astrocytes contribute to ALS progression and that blocking them can protect neurons and improve survival in ALS models.

bioRxiv · Mar 14, 2020 · PreprintNeuroscience

Role of human induced pluripotent stem cell-derived spinal cord astrocytes in the functional maturation of motor neurons in a multielectrode array system

Arens Taga, Raha Maryam Dastgheyb, Christa Whelan Habela, Jessica Joseph, Jean‐Philippe Richard, Sarah K. Gross, Giuseppe Lauria, Gabsang Lee, Norman J. Haughey, Nicholas John Maragakis

This paper develops a co-culture method for human iPSC-derived astrocytes and motor neurons in MEA systems, showing bidirectional maturation effects.

Stem Cells Translational Medicine · Oct 21, 2019Peer-reviewedNeuroscience