Christa Whelan Habela

This paper develops a human iPSC-derived microfluidic platform to model corticospinal tract connectivity and pathology for neurodegenerative disease research.

This study examines 15q11.2 deletion effects on neuronal development and function using iPSC-derived neurons, finding structural and functional impairments in network connectivity and maturation.

The paper identifies the spatiotemporal coordination of WAVE and N-WASP with actin-bundling proteins to generate invasive protrusions during cell-cell fusion.

This study identifies branched actin polymerization as essential for myoblast fusion during skeletal muscle regeneration, showing its role in forming invasive protrusions for fusion.

The paper analyzes phase-amplitude coupling in human 2D neural cultures to show that network-level interactions, not single neurons, drive coupling, suggesting PAC is a fundamental property of neural networks.

This study shows that Cyfip1 is critical for maintaining the adult subventricular zone niche by regulating B1 cell proliferation and adherens junction proteins.

This paper develops a co-culture method for human iPSC-derived astrocytes and motor neurons in MEA systems, showing bidirectional maturation effects.